Estimating Genome-Wide Copy Number Using Allele-Specific Mixture Models
نویسندگان
چکیده
منابع مشابه
Estimating Genome-Wide Copy Number Using Allele Specific Mixture Models
Genomic changes such as copy number alterations are one of the major underlying causes of human phenotypic variation among normal and disease subjects. Array comparative genomic hybridization (CGH) technology was developed to detect copy number changes in a high-throughput fashion. However, this technology provides only a >30-kb resolution, which limits the ability to detect copy number alterat...
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ژورنال
عنوان ژورنال: Journal of Computational Biology
سال: 2008
ISSN: 1066-5277,1557-8666
DOI: 10.1089/cmb.2007.0148